Faculties of University Bonn: Fakultäten der Universität Bonn: Recent submissions
Now showing items 261-280 of 9379
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Rapid and epileptogenic astrocyte morphology changes in the hippocampus
(2025-03-25)Alterations in astrocytes are believed to contribute to the emergence and maintenance of epileptic activity. It has been demonstrated that astrocyte morphology in the hippocampus undergoes rapid changes within minutes ... -
How to Fulfil the UN Sustainability Goals: Rethinking the Role and Concept of Money in the Light of Sustainability
(2025-03-25)The cumulative dissertation consists of two publications, which complement each other. The main work is a book of 356 pages published by Springer Nature, which is a complex treatise on the role and concept of money in the ... -
The role of the purinergic receptor P2Y12 in Alzheimer's disease
(2025-03-25)Alzheimer’s disease (AD), the most common cause of dementia, shows a significant rise in prevalence due to increased global life expectancy and represents a major public health, social, and economic burden. Microglia, the ... -
Analysen der Akuttherapie und Komplikationen von ischämischen Schlaganfällen
(2025-03-25)Der Schlaganfall ist weltweit eine der führenden Ursachen für Mortalität und erworbene Behinderungen. Das klinische Outcome nach einem Schlaganfall kann mittels Behandlung auf der Stroke Unit einschließlich der Akuttherapie ... -
Antikonvulsive Wirkung der Elektrokrampftherapie: Effekt der Energiedosis, des Postiktalen Suppressionsindex und der Krampfdauer auf den Therapieerfolg
(2025-03-24)Die Elektrokonvulsionstherapie (EKT) ist ein wirksames Verfahren zur Behandlung therapieresistenter Depressionen und weiterer psychiatrischer Erkrankungen, bei dem unter Kurznarkose ein therapeutischer Krampfanfall induziert ... -
Investigation of deep learning approaches for automated analysis in radiological cross-sectional imaging
(2025-03-24)Artificial intelligence (AI)-based methods are nowadays an integral part of medical research and are also applied in radiology, for example, for the automation of quantitative image analysis. Automated evaluation tools are ... -
Distribution matters: Long-term quantification of the Sustainable Development Goals with household detail for different socio-economic pathways
(2024-07-02)Knowledge about upcoming sustainability challenges is crucial to tackle them by political incentives, not at least to reach the United Nations’ 17 Sustainable Development Goals (SDGs). SDGs are multidimensional and require ... -
Characterizing a novel hepatic NK-like T cell population and defining its function during antiviral immune response
(2025-03-24)The family of NK-like (NK1.1+) T cells is extremely heterogeneous, with the most predominant members being the type-I and type-II NKT cells. In addition to that, other unconventional T cells, like gamma-delta T and MAIT ... -
Chirurgischer Aortenklappenersatz versus Implantation einer Katheterklappe - Untersuchung zur kurzfristigen und kognitiven Funktion bei Hochrisikopatienten
(2025-03-24)In dieser prospektiven Studie wurde die kurzfristige neurologische und kognitive Funktion nach chirurgischem Aortenklappenersatz (AKE) von 30 Risikopatienten untersucht. Als Kontrollgruppe wurden 30 Patienten nach ... -
Prognostischer Nutzen der Evaluation von Akutkomplikationen mittels kardialer Magnetresonanztomographie bei Tako-Tsubo-Syndrom
(2025-03-24)Ziele: Ziel dieser Arbeit war es mittels kardialer Magnetresonanztomographie (CMR) einfach zu erfassende bildgebende Merkmale zu finden, die mit dem Auftreten von schwerwiegenden unerwünschten kardiovaskulären Ereignissen ... -
Optogenetische Aktivierung des Gi-Signalwegs ermöglicht eine zeitlich präzise Modulation der Schrittmacheraktivität von Kardiomyozyten
(2025-03-24)G-Protein-Signalwege spielen eine zentrale Rolle in der Regulation der kardialen Funktion unter physiologischen und pathophysiologischen Bedingungen. Ihre funktionelle Analyse mittels optogenetischer Techniken, die eine ... -
Design and Multistep Synthesis of Ligands for the GPR18 and GPR183: Related Orphan G Protein-Coupled Receptors with Immunoregulatory Functions
(2025-03-24)(noch nicht zugänglich / not yet accessible) -
Klinischer Einsatz des Ultraschall-gesteuerten hoch-intensiven fokussierten Ultraschalls zur Behandlung von Desmoidtumoren
(2025-03-24)Desmoidtumore sind eine vergleichsweise seltene Tumorentität, die sporadisch oder im Zusammenhang mit der Familiären Adenomatösen Polyposis coli auftreten. Bei Desmoiden handelt es sich um semi-maligne Weichgewebstumore, ... -
Exploring and Addressing General Limitations of Compound Potency Predictions using Machine Learning
(2025-03-24)Compound potency prediction is a major task in computational drug discovery. Regression models based on machine learning (ML) approaches have become popular for small molecule potency predictions. Recently, deep learning ... -
Choriokapillaris-Flussausfälle bei Patienten mit Pseudoxanthoma elasticum
(2025-03-20)<strong>Ziel: </strong> Die Quantifizierung von sekundären Choriokapillaris-Flussausfällen bei Patienten mit Pseudoxanthoma elasticum (PXE) im präatrophen Frühstadium der Erkrankung, in Korrelation mit morphologischen ... -
Ripple-locked coactivity of stimulus-specific neurons and human associative memory
(2024-02-16)Associative memory enables the encoding and retrieval of relations between different stimuli. To better understand its neural basis, we investigated whether associative memory involves temporally correlated spiking of ... -
Properly capturing tariff rate quotas for trade policy analysis in computable general equilibrium models
(2021-08-19)Computable general equilibrium (CGE) models are generally used to conduct trade policy analysis; however, given the complexity in data collection and modeling, tariff rate quotas (TRQs) are often simplified in these models. ... -
It is all in the details: A bilateral approach for modelling trade agreements at the tariff line
(2021-03-08)Policymakers are increasingly relying on computable general equilibrium (CGE) models to provide economy-wide impacts of trade agreements; however, these assessments often make the simplifying assumption of complete bilateral ... -
Price Differences Between Organic and Conventional Products in E-Commerce
(2025-03-17)The global market for organic foods is expanding, with consumers willing to pay more for their perceived health and sustainability benefits. However, expressing willingness to pay does not guarantee that sellers can charge ... -
Markups and export behavior: Firm-level evidence from the French food processing industry
(2022-01-24)The relationship between a firm's markups and its export behavior is highly relevant to individual firms' strategic decisions as well as to governments' policies regarding competition. We investigate the impact of markups ...
