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Now showing items 1966-1985 of 10483
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Cell-cell adhesion mediated by mobile receptor-ligand pairs: a biomimetic study
Fenz, Susanne Franziska (2009-05-07)This thesis aims at a quantitative understanding of the physical processes in cell-cell adhesion caused by mobile cell adhesion molecules. To unequivocally separate physical processes from active biological cell response, ... -
Cellular and molecular defence mechanisms against Legionella infection
Oberkircher, Lara Marie (2024-01-26)The two most prevalent causes of Legionnaires’ disease are <em>L. pneumophila</em> and <em>L. longbeachae</em>. The rising incidence of the Legionnaires’ disease over the past two decades together with the increasing ... -
Cellular and molecular mechanisms of ANCA-associated vasculitis
Kessler, Nina (2023-07-12)ANCA-associated vasculitides (AAV) are a group of life-threatening autoimmune diseases that lead to necrotizing inflammation of the small and medium-sized blood vessels in various organs. Pulmonary hemorrhages are associated ... -
Cellular and synaptic correlates of learning and memory and their impairment in a mouse model of Alzheimer's disease
Poll, Stefanie (2017-11-28)Alzheimer's disease (AD) is characterized by synaptic dysfunction and progressive memory loss. The hippocampus is indispensable for memory processes and early affected by disease-associated pathology. It is still debated ... -
Cellular biomechanics in 2D and 3D epithelial model tissues: from keratin intermediate filaments to breast gland in vitro reconstructed basement membranes
Fabris, Gloria (2017-01-24)<p>The mechanical organization of biological tissue is crucial to the load-transmitting capacity of our bodies, and follows a hierarchical architecture that macroscopically results in organ’s formation and function. At the ... -
Cellular energy supply and aging in dairy cows: Characterization of different physiological states and impact of diet-induced over-condition
Laubenthal, Lilian (2015-09-24)Lactation in dairy cows is accompanied by dramatic changes in energy balance and thus requires the continued adaption of the key organs, namely adipose tissue (AT), liver, and mammary gland to the varying conditions. The ... -
Cellular Influx and Cytotoxicity of Oxaliplatin Analogues
Buß, Irina (2010-10-08)This thesis describes the first systematic investigation of the relationship between lipophilicity and reactivity on the one hand and cellular accumulation and cytotoxic activity on the other hand of a new class of oxaliplatin ... -
Cellular mechanoresponse to extracellular matrix shear strain and stiffness studied in a cell culture model of breast gland development
Friedland, Florian (2023-05-12)Mechanobiological regulation is a crucial element for tissue development and homeostasis. Dysregulation of the normal mechanobiological microenvironment of cells is linked to disease and negatively affects cancer patients' ... -
A census on the gas content of star-forming galaxies over the past 11 billion years of the universe
Wang, Tsan-Ming (2024-07-17)With the advent of the Atacama Large Millimeter/submillimeter Array (ALMA), we now have the opportunity to measure the physical properties of the cold, dense, star-forming interstellar medium (ISM) even in distant, ... -
Centralisers of polynomially growing automorphisms of free groups
Rodenhausen, Moritz (2013-07-31)The main theorem of this thesis asserts that many centralisers in the automorphism groups Aut(F_n) and Out(F_n) of the free group F_n satisfy finiteness property VF, i.e. these centralisers have a finite index subgroup ... -
Ceramide im Plasma und ihre Rolle bei Patienten mit koronarer Herzkrankheit und Diabetes mellitus Typ 2
Heinrich, Nadine Ningning (2024-02-21)Ceramide sind Sphingolipide, die unter anderem eine essenzielle Rolle als Mediatoren auf zellulärer Ebene in inflammatorischen Prozessen spielen. Hierzu gehören beispielsweise die koronare Herzkrankheit (KHK) und der ... -
Ceramide Synthase in Transcriptional Regulation and Lipid Sensing
Sociale, Mariangela (2019-05-20)Ceramide synthases (CerS) are highly conserved transmembrane proteins necessary for sphingolipid biosynthesis. CerSs carry a TLC (Tram-Lag1-CLN8) domain, containing a conserved Lag1p motif required for ceramide synthesis. ... -
Chalkogenanthrene und Übergangsmetallhalogenide – Komplexbildung und Redox-Reaktionen
Bockshecker, Michael (2015-12-01)In der vorliegenden Arbeit wurde das Reaktionsverhalten der Chalkogenanthrene Thianthren (TA), Selenanthren (SeA) und Phenoxathiin (PhA) gegenüber Lewis-sauren Metallhalogeniden der Summenformel MX<sub>5</sub> (M = Nb, Ta; ... -
Chalkogenpolykation-Halogenidobismutate: Salzartige Verbindungen mit hoher struktureller Komplexität
Eck, Steffen Jan (2010-04-14)Im Rahmen der vorliegenden Arbeit wurden Chalkogenpolykation-Halogenidobismutate dargestellt, ihre Struktur durch Röntgenstrahlungsbeugung bestimmt und ihre physikalischen Eigenschaften untersucht. Dabei wurden neue ... -
The Challenge of Governing Natural Resources: A Social Network Analysis of Actors’ Collaboration in Ghana’s Petroleum Sector
Rapp, Johanna (2017-07-20)The PhD thesis investigates the extent of collaboration among actors in Ghana’s petroleum sector. Previous research has either focused on the socio-economic changes enforced upon local communities in close proximity to the ... -
Challenges and Opportunities for the Inclusion of Women in Politics in Pakistan: A Case Study of Women and Men Career Politicians in the Pakistan Tehreek Insaf Political Party (PTI)
Hussain, Madiha (2022-02-08)The present study inquired into the challenges and opportunities pertaining to women’s political participation beyond elections in Pakistan. The main objective of the current research was to explore how women who pursue ... -
Challenges and opportunities of using ecological and remote sensing variables for crop pest and disease mapping
Kyalo, Richard (2019-07-15)Crop pest and diseases are responsible for major economic losses in the agricultural systems in Africa resulting in food insecurity. Potential yield losses for major crops across Africa are mainly caused by pests and ... -
Challenges and present fields of action at laser scanner based deformation analyses
Holst, Christoph; Kuhlmann, Heiner (2016-03-31)Due to improved laser scanning technology, laser scanner based deformation analyses are presently widespread. These deformation analyses are no longer based on individual points representing the deformation of an object ... -
The challenges of rural youth employment in Africa: a literature review
Kubik, Zaneta (2022-05)This paper provides a literature review on youth employment challenges in rural Africa. The rapidly changing demographic structure across the continent is expected to have important economic and social consequences, ... -
Challenges of theoretical and numerical structure formation in a ΛCDM universe
Roth, Nina (2015-06-22)Systematic surveys of the extra-galactic sky have revealed the existence of large-scale structures in the Universe: the galaxy distribution is organized in a complex network of filaments surrounding underdense regions and ...