Mathematisch-Naturwissenschaftliche Fakultät: E-Dissertationen
Neueste Zugänge
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Pharmacological and structural investigations of the ATP-gated ion channel receptor P2X4
(2025-06-17)(noch nicht zugänglich / not yet accessible) -
Untersuchungen zur Bestimmung der minimalen selektiven Konzentration von Antibiotika und Schwermetallen
(2025-06-12)Die vorliegende Arbeit besteht aus zwei Komponenten. Der erste Teil dieser Arbeit war im interdisziplinären Verbundprojekt HyReKA verortet und bot Unterstützung der Feldarbeit durch Laborwerte. Denn zum Zeitpunkt der Arbeit ... -
Population Synthesis of Evolved Massive Binary Stars in the Magellanic Clouds
(2025-06-12)Massive stars are crucial building blocks of the Universe. They produce heavy elements, drive the evolution of galaxies, and are the origin of spectacular events such as supernovae and gravitational-wave coalescences. While ... -
Human Aspects in Secure Messaging
(2025-06-05)The widespread adoption of digital communication demands robust security and privacy protections, particularly through secure messaging systems that can protect personal and sensitive information. Despite advancements in ... -
Detecting Superfluids, Exciting the Higgs Mode and Enhanced Cooling of Dimers in the BEC-BCS Crossover
(2025-06-04)In this thesis, the BEC-BCS crossover is experimentally investigated using a quantum simulator apparatus. We prepare a degenerate, interacting fermionic sample by cooling atoms in two of the lowest hyperfine states of ... -
Impact of non-neuronal mechanisms on synaptic transmission
(2025-06-03)The brain receives, encodes and shares information between neurons via synaptic transmission. This kind of communication is generally exclusive to neurons, and was soon found to be activity-dependent and therefore plastic. ... -
Studies of the Envelopes of Evolved Stars using Millimetre and Submillimetre Spectroscopy
(2025-06-03)Asymptotic giant branch (AGB) stars are low- to intermediate-mass stars at the end of their life. At this stage of stellar evolution, these objects shed large amounts of matter in the form of gas and dust, forming a ... -
Identification of compensatory mechanisms and disease pathways in mitochondrial disease and synucleinopathy
(2025-06-02)Mitochondria play vital roles in a variety of processes such as cellular metabolism, intracellular signalling and cell death. Defects in mitochondria can lead to inherited metabolic disorders and neurodegenerative diseases. ... -
Design and development of probes for studying cannabinoid and related orphan G protein-coupled receptors and their signaling
(2025-05-27)G protein-coupled receptors (GPCRs) are the largest family of human membrane proteins and represent one of the most important classes of pharmacological targets for drugs. Among these, the cannabinoid (CB)receptor subtypes ... -
Modelling Molecular Gas and Its Tracers Across Cosmic Time
(2025-05-27)Our understanding of the distant Universe and the processes governing galaxy formation and evolution largely stems from observing the light from stars and its interaction with the material surrounding them. However, an ... -
Glucose-induced activation of Tas1R3 disrupts calcium signaling and macrophage functionality
(2025-05-22)The incidence of <em>diabetes mellitus</em> has risen alarmingly in recent years, becoming one of the leading causes of death worldwide. The disease is characterized by hyperglycemia, increased blood glucose levels, and ... -
Mechanism of Action Analyses of Cell Wall Synthesis Inhibitors and Lipophilic Derivatives with Enhanced Antibiotic Activity
(2025-05-21)(noch nicht zugänglich / not yet accessible) -
Investigation of β-arrestin 2 recruitment, downstream signal transduction and lateral mobility of adenosine A1 receptor after treatment with valerian extract Ze 911
(2025-05-21)Sleep is a complex physiological process with a variety of molecules involved. Even though a lot of research and progress has been made until today, the exact underlying mechanism still eludes us. Many people must deal ... -
Context-aware Deep Learning in Medical Image Analysis
(2025-05-13)Deep Learning (DL) has demonstrated outstanding performance in the area of medical image analysis, with models achieving levels of accuracy that may exceed those of human experts across various applications. This highlights ... -
Dense Gas and Star Formation from the Milky Way to Nearby Galaxies
(2025-05-12)Galaxies are the building blocks of the universe, which come in different sizes and shapes. Driven by dark matter, galaxies can interact and merge to form bigger galaxies across cosmic time. Across the cosmos, there are ... -
Reduced Costs for Vehicle Routing and General Mixed-Integer Programs
(2025-05-09)Mixed-integer linear programming is a powerful tool for modeling combinatorial optimization problems in a standardized way. Sophisticated solvers that calculate optimal solutions for these programs consist of dozens of ... -
Investigating the Conformational Landscape of Cas13a
(2025-05-06)Bacteria and bacteriophages are in a constant arms race to develop strategies to coexist. One adaptive defense system, which bacteria and archaea have developed against phages is the CRISPR-Cas (Clustered Regularly Interspaced ... -
Effects of structural differences of biflavonoids from fruits of the Brazilian peppertree (Schinus terebinthifolius Raddi) on food-associated microorganisms
(2025-05-05)Economic, health, or sensory aspects are affected by microbial contamination of food. The preservation of food is crucial for ensuring food safety and reducing economic losses. With increasing resistance, allergies, and ... -
Omics-driven Drug Repurposing and Treatment Assessment in Human Viral Diseases
(2025-05-02)In this cumulative thesis, I present my research on transcriptomic-based drug repurposing in human viral infections describing an optimized workflow for drug prediction, <em>in vitro</em> validation and <em>in vivo</em> ... -
Economic geographies of large-scale renewable energies development in Kenya: Financing, governance and infrastructures
(2025-05-02)Energy transition theories and studies have made important contributions to our knowledge of the challenges and possibilities for achieving sustainable energy transition and more sustainable societies. However, this body ...
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